Overview
What it is.
This blend pairs a GHRH analog (CJC-1295) with a selective secretagogue (Ipamorelin) — two complementary signals studied together for their action on the body's own pulsatile growth hormone release. It's the combination most frequently referenced in GH-axis research protocols.
Research Areas
- Studied for complementary action on natural growth hormone release
- Studied for its potential role in recovery and sleep-quality research
- Studied for its potential role in body-composition research alongside diet and exercise variables
Batch & Testing
Proof, not promises.
COA ships with every order
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Research Deep-Dive
How it works.
Research Deep-Dive
How it works.
This is the pairing of two individually studied peptides — CJC-1295, a long-acting GHRH analog, and ipamorelin, a selective ghrelin-receptor secretagogue — compounded together rather than a novel molecule in its own right. It is the combination licensed U.S. compounding pharmacies formulate most often for growth-hormone-support protocols.
CJC-1295 activates the GHRH receptor while ipamorelin activates the separate ghrelin (GHS-R1a) receptor; together they deliver two independent "go" signals that converge on the pituitary's own GH-release machinery, producing a larger combined pulse than either compound tends to on its own, while ipamorelin's receptor selectivity limits the cortisol and prolactin rise seen with older secretagogues.
Use Cases Explored
- Studied for complementary action on natural growth hormone release across two independent receptor pathways
- Studied for its potential role in recovery and sleep quality
- Studied for its potential role in body composition alongside diet and exercise
The Evidence
Each component has its own human dosing data
CJC-1295's GH/IGF-1-raising effect was shown in randomized, placebo-controlled trials in healthy adults, and ipamorelin's selective GH-release profile (without meaningful cortisol/prolactin rise) was shown in preclinical models and small human PK/PD studies — real evidence for each half of the pairing individually.
The combination itself has not been through its own placebo-controlled trial
The rationale for combining GHRH-receptor and ghrelin-receptor agonists is grounded in receptor pharmacology and is the most common formulation licensed pharmacies compound, but there is no dedicated randomized trial testing the CJC-1295 + ipamorelin combination itself against either component alone.
Neither component has completed a full FDA drug-approval program
CJC-1295 never reached approval (its later Phase II lipodystrophy trial was discontinued after a subject death, judged unrelated to treatment) and ipamorelin's development also ended before approval — so this remains a compounded off-label combination, not an FDA-reviewed product.
Specifications
The essentials.
Specifications
The essentials.
- Form
- Lyophilized powder
- Storage
- Store in a cool, dry place. Refrigerate at 2–8°C after reconstitution
- Shelf life
- 24 months lyophilized; 4–6 weeks refrigerated after reconstitution
- Solubility
- Reconstitute with bacteriostatic water
- Vial capacity
- 3 ml glass vial
Blend Components
Questions
CJC-1295 / Ipamorelin FAQ
Questions
CJC-1295 / Ipamorelin FAQ
What is the CJC-1295 / Ipamorelin blend studied for?+
This blend is studied for complementary action on natural growth hormone release, and for its potential role in recovery, sleep-quality, and body-composition research alongside diet and exercise variables.
Why are CJC-1295 and Ipamorelin studied together rather than separately?+
They act on different parts of the same GH-axis signaling pathway, which is why researchers frequently formulate and study them together for complementary coverage.
What's the exact composition of this blend?+
The 10 mg vial is formulated at a 1:1 ratio — 5 mg CJC-1295 (no DAC) and 5 mg Ipamorelin.
How should this blend be handled and stored?+
It ships as a lyophilized powder. Reconstitute with bacteriostatic water and refrigerate at 2–8°C after mixing — good for roughly 4–6 weeks refrigerated, or up to 24 months unreconstituted in a cool, dry place.
Blends & Stacks
CJC-1295 / Ipamorelin
The standard GH-support research combination
The most widely studied GH-axis research combination — a GHRH analog paired with a selective secretagogue.
Size
Multi-vial pricing
Per-vial pricing, applied automatically. No code needed.
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All products sold by One Tap Peptides are intended for laboratory research use only. Not for human consumption. Not intended for animal use. Not intended for diagnostic or therapeutic purposes.
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