Overview
What it is.
This blend pairs a GHRH analog (CJC-1295) with a selective secretagogue (Ipamorelin) — two complementary signals studied together for their action on the body's own pulsatile growth hormone release. It's the combination most frequently referenced in GH-axis research protocols.
Research Areas
- Studied for complementary action on natural growth hormone release
- Studied for its potential role in recovery and sleep-quality research
- Studied for its potential role in body-composition research alongside diet and exercise variables
Batch & Testing
Proof, not promises.
COA ships with every order
Every batch we release is independently HPLC tested before it ever reaches a lab bench. Browse the full certificate library.
Research Deep-Dive
How it works.
Research Deep-Dive
How it works.
This is the pairing of two individually studied peptides — CJC-1295, a long-acting GHRH analog, and ipamorelin, a selective ghrelin-receptor secretagogue — compounded together rather than a novel molecule in its own right. It is the combination licensed U.S. compounding pharmacies formulate most often for growth-hormone-support protocols.
CJC-1295 activates the GHRH receptor while ipamorelin activates the separate ghrelin (GHS-R1a) receptor; together they deliver two independent "go" signals that converge on the pituitary's own GH-release machinery, producing a larger combined pulse than either compound tends to on its own, while ipamorelin's receptor selectivity limits the cortisol and prolactin rise seen with older secretagogues.
Use Cases Explored
- Studied for complementary action on natural growth hormone release across two independent receptor pathways
- Studied for its potential role in recovery and sleep quality
- Studied for its potential role in body composition alongside diet and exercise
The Evidence
Each component has its own human dosing data
CJC-1295's GH/IGF-1-raising effect was shown in randomized, placebo-controlled trials in healthy adults, and ipamorelin's selective GH-release profile (without meaningful cortisol/prolactin rise) was shown in preclinical models and small human PK/PD studies — real evidence for each half of the pairing individually.
The combination itself has not been through its own placebo-controlled trial
The rationale for combining GHRH-receptor and ghrelin-receptor agonists is grounded in receptor pharmacology and is the most common formulation licensed pharmacies compound, but there is no dedicated randomized trial testing the CJC-1295 + ipamorelin combination itself against either component alone.
Neither component has completed a full FDA drug-approval program
CJC-1295 never reached approval (its later Phase II lipodystrophy trial was discontinued after a subject death, judged unrelated to treatment) and ipamorelin's development also ended before approval — so this remains a compounded off-label combination, not an FDA-reviewed product.
Specifications
The essentials.
Specifications
The essentials.
- Vial Capacity
- 3 ml glass vial
- Form
- Lyophilized powder
- Solubility
- Reconstitute with bacteriostatic water
- Storage
- Store in a cool, dry place. Refrigerate at 2–8°C after reconstitution
- Shelf Life
- 24 months lyophilized; 4–6 weeks refrigerated after reconstitution
Blend Components
Questions
CJC-1295 / Ipamorelin FAQ
Questions
CJC-1295 / Ipamorelin FAQ
Why are CJC-1295 and Ipamorelin studied together rather than separately?+
They act on different parts of the same GH-axis signaling pathway, which is why researchers frequently formulate and study them together for complementary coverage.
Blends & Stacks
CJC-1295 / Ipamorelin
The standard GH-support research combination
The most widely studied GH-axis research combination — a GHRH analog paired with a selective secretagogue.
Size
COA-backed guarantee — independently test any vial; if it's under 99% purity, full refund + testing costs covered.
All products sold by One Tap Peptides are intended for laboratory research use only. Not for human consumption. Not intended for animal use. Not intended for diagnostic or therapeutic purposes.
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