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Overview

What it is.

Selank is a synthetic peptide developed by Russian researchers with its own regulatory research history there, studied for stress-response and cognitive-performance-related pathways.

Research Areas

  • Studied for its potential role in stress- and anxiety-related-pathway research
  • Studied for its potential role in cognitive-performance research
  • Studied primarily within Russian pharmacological research literature

Batch & Testing

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Research Deep-Dive

How it works.

Selank is a synthetic peptide, structurally related to a natural immune peptide called tuftsin, developed by Russian researchers and registered there since 2009 as a prescription anti-anxiety medication. It has one of the more substantial human clinical trial records of any peptide discussed online — almost all of it conducted within the Russian medical research system.

Selank is studied for effects on GABA-A receptor signaling, similar in principle to how benzodiazepine anti-anxiety medications work, along with effects on brain-derived neurotrophic factor (BDNF) expression and serotonin pathways in animal models. Its dual mechanism — a fast-acting GABA effect and slower neuroplasticity-related effects — is offered as an explanation for why its research profile differs from standard anti-anxiety drugs.

Use Cases Explored

  • Studied in Russian clinical trials for generalized anxiety disorder and neurasthenia
  • Studied for its interaction with GABAergic signaling pathways
  • Studied in animal models for effects on BDNF expression tied to neuroplasticity
  • Studied as a comparator to benzodiazepine medications in Russian trial populations

The Evidence

Russian randomized comparator trial (Zozulya et al., 2008)

A 62-patient trial compared Selank to the benzodiazepine medazepam in generalized anxiety disorder and neurasthenia; Selank matched medazepam on standard anxiety rating scales while researchers reported fewer sedative side effects — but the trial was conducted, published, and never independently replicated outside Russia.

Broader Russian clinical literature (~800+ patients cumulative)

Published Russian trials over roughly two decades report anxiolytic effects across GAD, neurasthenia, and cognitive-complaint populations, along with a low reported rate of dependence or withdrawal — but these findings have not been validated through large, multi-center, placebo-controlled Western trials with pre-registered endpoints.

Animal-model mechanistic research

Rodent studies link Selank to increased hippocampal BDNF expression and altered gene expression in GABAergic neurotransmission pathways — mechanistic groundwork, not human proof of the same effects.

Specifications

The essentials.

Form
Lyophilized powder
Storage
Store in a cool, dry place. Refrigerate at 2–8°C after reconstitution
Shelf life
24 months lyophilized; 4–6 weeks refrigerated after reconstitution
Solubility
Reconstitute with bacteriostatic water
Vial capacity
3 ml glass vial

Questions

Selank FAQ

What is Selank studied for?+

Selank is studied for its potential role in stress- and anxiety-related-pathway research and cognitive-performance-related pathways, primarily within Russian pharmacological research literature.

How is Selank related to Semax, also sold here?+

Both come from the same Russian research lineage and are often studied together, but they're distinct sequences with different research emphases — Selank leans toward stress-response research, Semax toward cognitive and neuroprotective research.

How should Selank be handled and stored?+

It ships as a lyophilized powder. Reconstitute with bacteriostatic water and refrigerate at 2–8°C after mixing — good for roughly 4–6 weeks refrigerated, or up to 24 months unreconstituted in a cool, dry place.

What testing does this batch undergo?+

Every batch is HPLC tested for purity and identity, plus sterility and endotoxin screening, before release. The Certificate of Analysis for that lot ships with your order.

Neuro

Selank

A synthetic peptide developed in Russia, studied there for stress- and cognition-related research.

$35· $7.00/mg

Size

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Bacteriostatic Water

Bacteriostatic Water

Required for reconstitution. Learn more →

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All products sold by One Tap Peptides are intended for laboratory research use only. Not for human consumption. Not intended for animal use. Not intended for diagnostic or therapeutic purposes.