Overview
What it is.
TB-500 is a synthetic version of Thymosin Beta-4, a protein the body produces naturally that plays a role in cell structure and movement. It draws research interest for its involvement in wound- and tissue-repair signaling.
Research Areas
- Studied for its potential role in wound-healing signaling
- Studied for its potential role in cell-migration research during tissue repair
- Studied for its interaction with actin, a structural protein in cells
Batch & Testing
Proof, not promises.
COA ships with every order
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Research Deep-Dive
How it works.
Research Deep-Dive
How it works.
TB-500 is the name commonly used for injectable products marketed as a version of Thymosin Beta-4 (Tβ4), a protein the body produces naturally that plays a role in cell structure, movement, and wound-repair signaling. It's important to separate two things that get conflated: pharmaceutical-grade, regulated Tβ4 that has been through real clinical trials, and the unregulated "TB-500" injectable products sold online — those are not the same evidence base.
Thymosin Beta-4 binds actin, a structural protein that helps cells move, and is believed to support cell migration to wound sites, new blood vessel formation, and reduced inflammation — mechanisms studied in both topical dermal-healing research and, in a separate program, corneal-healing research.
Use Cases Explored
- Formal drug-development research into chronic wound healing (venous and pressure ulcers)
- Formal drug-development research into corneal wound healing
- Preclinical research into cell-migration and actin-binding mechanisms
The Evidence
Phase 1 safety trial (topical Tβ4, 15 healthy volunteers)
A 28-day topical dosing trial found no significant adverse events and good tolerability — an early safety signal, not an efficacy result.
Phase 2 chronic-wound trials (topical Tβ4)
In venous stasis and pressure ulcer patients, topical Tβ4 accelerated healing time in patients who healed and showed roughly 25% complete wound closure at 3 months in one venous-ulcer trial — described by researchers as modest by pharmaceutical standards, not a dramatic effect.
Most advanced program: corneal healing
A Phase 3 trial (SEER-1) in neurotrophic keratopathy found complete corneal healing in 60% of patients on Tβ4 versus 12.5% on placebo — the strongest clinical data behind the molecule, but for corneal injury specifically, not for the tendon/muscle/ligament uses TB-500 is typically marketed for online.
Critical caveat on injectable TB-500
The clinical trial data above is for regulated, pharmaceutical-grade topical Tβ4 formulations. Injectable products sold as "TB-500" have not been tested in any completed Phase 2 or Phase 3 trial for tendon, muscle, or ligament injury and carry no equivalent regulatory oversight or safety data.
Specifications
The essentials.
Specifications
The essentials.
- Form
- Lyophilized powder
- Storage
- Store in a cool, dry place. Refrigerate at 2–8°C after reconstitution
- Shelf life
- 24 months lyophilized; 4–6 weeks refrigerated after reconstitution
- Solubility
- Reconstitute with bacteriostatic water
- Vial capacity
- 3 ml glass vial
Questions
TB-500 FAQ
Questions
TB-500 FAQ
What is TB-500 studied for?+
TB-500 is studied for its involvement in wound- and tissue-repair signaling, examined in research models for cell-migration activity and interaction with actin, a structural protein in cells.
What is TB-500 synthesized from?+
It's a synthetic version of Thymosin Beta-4 (Tβ4), a protein the body produces naturally that plays a role in cell structure and movement.
How should TB-500 be handled and stored?+
It ships as a lyophilized powder. Reconstitute with bacteriostatic water and refrigerate at 2–8°C after mixing — good for roughly 4–6 weeks refrigerated, or up to 24 months unreconstituted in a cool, dry place.
What testing does this batch undergo?+
Every batch is HPLC tested for purity and identity, plus sterility and endotoxin screening, before release. The Certificate of Analysis for that lot ships with your order.
Tissue Repair
TB-500
Thymosin Beta-4, Tβ4
A synthetic version of a naturally occurring repair-signaling protein, studied in tissue research.
Size
Multi-vial pricing
Per-vial pricing, applied automatically. No code needed.
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All products sold by One Tap Peptides are intended for laboratory research use only. Not for human consumption. Not intended for animal use. Not intended for diagnostic or therapeutic purposes.
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