Overview
What it is.
CJC-1295 is a GHRH analog engineered for a longer half-life than sermorelin. It is frequently formulated alongside a growth-hormone-releasing peptide such as ipamorelin for research into complementary signaling along the same GH-axis pathway.
Research Areas
- Studied for its potential role in sustaining natural growth hormone pulses
- Studied for its potential role in recovery-pathway research
- Studied for its potential role in lean body-composition research
- Studied for its potential role in sleep-quality research
Batch & Testing
Proof, not promises.
COA ships with every order
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Research Deep-Dive
How it works.
Research Deep-Dive
How it works.
CJC-1295 is a modified GHRH analog engineered for a much longer half-life than sermorelin, achieved by linking the active peptide fragment to a drug affinity complex (DAC) that binds circulating albumin. It's most often compounded alongside a growth-hormone-releasing peptide such as ipamorelin.
Like sermorelin, CJC-1295 activates the pituitary's GHRH receptor to stimulate the body's own GH release. The DAC modification and resistance to enzymatic breakdown extend its activity from hours to days, producing a sustained rise in GH and IGF-1 rather than a single short pulse.
Use Cases Explored
- Studied for its potential role in sustaining natural growth hormone pulses over a longer window than shorter-acting GHRH analogs
- Studied for its potential role in training recovery
- Studied for its potential role in lean body composition alongside diet and exercise
- Studied for its potential role in sleep quality
The Evidence
Randomized, placebo-controlled human dosing trials (Teichman et al., 2006)
Two randomized, double-blind, placebo-controlled ascending-dose trials in healthy adults found single injections raised GH 2- to 10-fold for 6+ days and IGF-1 1.5- to 3-fold for 9-11 days, with a cumulative effect across repeat dosing — real controlled human data, though from a short-term healthy-volunteer population, not a therapeutic-outcome trial.
Phase II lipodystrophy/GHD trial discontinued after a subject death
A later clinical program studying CJC-1295 for lipodystrophy and growth hormone deficiency was halted after a trial subject died; the investigator attributed it to unrelated coronary artery disease, but the sponsor stopped development as a precaution. A separate planned trial in HIV-associated visceral adiposity was also discontinued during recruitment with no results reported.
No FDA-approved product or label exists
Despite the positive dosing-trial data, CJC-1295 never completed development into an approved drug — its evidence base stops at Phase I/II, and there is no FDA label defining an approved dose, indication, or long-term safety profile.
Specifications
The essentials.
Specifications
The essentials.
- Form
- Lyophilized powder
- Storage
- Store in a cool, dry place. Refrigerate at 2–8°C after reconstitution
- Shelf life
- 24 months lyophilized; 4–6 weeks refrigerated after reconstitution
- Solubility
- Reconstitute with bacteriostatic water
- Vial capacity
- 3 ml glass vial
Questions
CJC-1295 (no DAC) FAQ
Questions
CJC-1295 (no DAC) FAQ
Why is CJC-1295 often paired with another peptide in research protocols?+
It acts on the GHRH receptor while peptides like ipamorelin act on a separate growth-hormone-releasing pathway — researchers frequently study the two together for their complementary mechanism.
How does this no-DAC version differ from the CJC-1295 with DAC also sold here?+
The DAC modification binds albumin in circulation and extends the half-life well beyond this version — researchers studying pulsatile signaling closer to native GHRH release patterns tend to use the no-DAC form, while sustained-signaling research uses the DAC version.
How should CJC-1295 be handled and stored?+
It ships as a lyophilized powder. Reconstitute with bacteriostatic water and refrigerate at 2–8°C after mixing — good for roughly 4–6 weeks refrigerated, or up to 24 months unreconstituted in a cool, dry place.
What testing does this batch undergo?+
Every batch is HPLC tested for purity and identity, plus sterility and endotoxin screening, before release. The Certificate of Analysis for that lot ships with your order.
Growth Hormone
CJC-1295 (no DAC)
Modified GRF 1-29
A longer-acting GHRH analog frequently studied alongside selective secretagogues.
Size
Multi-vial pricing
Per-vial pricing, applied automatically. No code needed.
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All products sold by One Tap Peptides are intended for laboratory research use only. Not for human consumption. Not intended for animal use. Not intended for diagnostic or therapeutic purposes.
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