Overview
What it is.
GHRP-2 is a growth hormone secretagogue from an earlier generation of GHRPs. It reliably stimulates GH release in research models, and is also studied for its comparatively larger effect on cortisol and prolactin relative to newer, more selective secretagogues.
Research Areas
- Studied for its potential role in growth hormone secretion
- Studied for its potential role in appetite-related research
- Studied in comparison with more selective growth hormone secretagogues
Batch & Testing
Proof, not promises.
COA ships with every order
The Certificate of Analysis for your batch ships in the box with your order. We're publishing the certificate archive here next.
Research Deep-Dive
How it works.
Research Deep-Dive
How it works.
GHRP-2 (pralmorelin) is an early-generation growth hormone secretagogue and the only compound of its kind to ever receive approval from a national drug regulator anywhere in the world — Japan's PMDA approved it in 2004, but strictly as a diagnostic test for growth hormone deficiency, not as a standing therapy.
GHRP-2 activates the ghrelin receptor (GHS-R1a), triggering GH release from the pituitary. Compared with newer, more selective secretagogues, GHRP-2 also meaningfully raises ACTH, cortisol, and prolactin, which is the tradeoff researchers point to when comparing it against options like ipamorelin.
Use Cases Explored
- Studied for its potential role in growth hormone secretion, including as a diagnostic stimulation test
- Studied for its potential role in appetite stimulation
- Studied in comparison with more selective growth hormone secretagogues for its cortisol and prolactin effects
The Evidence
Approved as a diagnostic agent in Japan (2004)
Japan's PMDA approved pralmorelin as a diagnostic test for GH deficiency based on a multicenter randomized trial (N=120) validating a GH-response cutoff, plus an earlier validation study (N=85) — real regulatory approval, but for a one-time diagnostic injection, not ongoing use.
Failed Phase II therapeutic trials for short stature
A separate development track studying GHRP-2 as a growth-promoting therapy for GH-deficient children — including an intranasal formulation — increased endogenous GH secretion but did not translate into clinically significant height gains over 24 weeks, and that program was discontinued.
No FDA approval or U.S. trial program
GHRP-2 has never been approved by the FDA for any use and has no active U.S. clinical trials as of this writing; its only regulatory approval anywhere is Japan's narrow diagnostic indication.
Specifications
The essentials.
Specifications
The essentials.
- Form
- Lyophilized powder
- Storage
- Store in a cool, dry place. Refrigerate at 2–8°C after reconstitution
- Shelf life
- 24 months lyophilized; 4–6 weeks refrigerated after reconstitution
- Solubility
- Reconstitute with bacteriostatic water
- Vial capacity
- 3 ml glass vial
Questions
GHRP-2 FAQ
Questions
GHRP-2 FAQ
What is GHRP-2 studied for?+
GHRP-2 is studied as a growth hormone secretagogue from an earlier generation of GHRPs, examined for reliably stimulating GH release alongside a comparatively larger effect on cortisol and prolactin than more selective, newer compounds.
How does GHRP-2 compare with GHRP-6, also sold here?+
Both are earlier-generation secretagogues studied for GH release, but GHRP-2 is generally examined for a somewhat smaller appetite-stimulating effect than GHRP-6 — researchers often study the two side by side for comparative-pathway designs.
How should GHRP-2 be handled and stored?+
It ships as a lyophilized powder. Reconstitute with bacteriostatic water and refrigerate at 2–8°C after mixing — good for roughly 4–6 weeks refrigerated, or up to 24 months unreconstituted in a cool, dry place.
What testing does this batch undergo?+
Every batch is HPLC tested for purity and identity, plus sterility and endotoxin screening, before release. The Certificate of Analysis for that lot ships with your order.
Growth Hormone
GHRP-2
Pralmorelin
An earlier-generation growth-hormone-releasing peptide studied for GH stimulation.
Size
Multi-vial pricing
Per-vial pricing, applied automatically. No code needed.
Ships within 24 hours · $20 flat shipping · Free over $200
Pay simply and securely via Zelle or Apple Pay (Apple Cash) — instructions are emailed the moment you order. How payment works →
Satisfaction guarantee — if a batch's documentation doesn't check out, contact support and we'll make it right.
All products sold by One Tap Peptides are intended for laboratory research use only. Not for human consumption. Not intended for animal use. Not intended for diagnostic or therapeutic purposes.
Related
