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Overview

What it is.

MGF is a splice variant of the IGF-1 gene expressed specifically in response to mechanical stress on muscle tissue, such as resistance exercise or injury. It's studied for a distinct, locally triggered signaling role compared with systemic IGF-1 analogs.

Research Areas

  • Studied for its expression pattern following mechanical stress on muscle tissue
  • Studied for its potential role in localized muscle-repair signaling
  • Studied as a distinct splice variant within the broader IGF-1 growth-factor family

Batch & Testing

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Research Deep-Dive

How it works.

MGF (Mechano Growth Factor) is a splice variant of the IGF-1 gene, expressed specifically in muscle tissue in response to mechanical stress such as resistance exercise or injury — distinct from the systemic IGF-1 analogs elsewhere in this catalog.

Rather than circulating systemically like IGF-1 LR3, MGF is studied for a locally triggered expression pattern tied directly to mechanical loading on muscle fibers, which researchers examine for a role in initiating local muscle-repair signaling cascades.

Use Cases Explored

  • Studied for its expression pattern following mechanical stress on muscle tissue
  • Studied for its potential role in localized muscle-repair signaling
  • Studied as a distinct splice variant within the IGF-1 growth-factor family

The Evidence

Animal-model and cell-culture research

MGF's mechanically triggered expression pattern is documented mainly in animal and cell-culture studies; the synthetic peptide's behavior once administered exogenously is less thoroughly characterized than the endogenous splice variant's natural expression pattern.

Limited independent replication

Much of the foundational MGF literature comes from a small number of research groups, and independent replication in the broader research community remains limited.

Specifications

The essentials.

Form
Lyophilized powder
Storage
Store in a cool, dry place. Refrigerate at 2–8°C after reconstitution
Shelf life
24 months lyophilized; 4–6 weeks refrigerated after reconstitution
Solubility
Reconstitute with bacteriostatic water
Vial capacity
3 ml glass vial

Questions

MGF FAQ

What is MGF studied for?+

MGF is studied for its expression pattern following mechanical stress on muscle tissue and its potential role in localized muscle-repair signaling.

How is MGF different from IGF-1 LR3 or IGF-DES?+

MGF is a splice variant of IGF-1 expressed specifically in response to mechanical stress — such as resistance exercise or injury — while IGF-1 LR3 and IGF-DES are systemic IGF-1 analogs studied for broader, non-trigger-dependent signaling.

How should MGF be handled and stored?+

It ships as a lyophilized powder in a single 2 mg size. Reconstitute with bacteriostatic water and refrigerate at 2–8°C after mixing — good for roughly 4–6 weeks refrigerated, or up to 24 months unreconstituted in a cool, dry place.

What testing does this batch undergo?+

Every batch is HPLC tested for purity and identity, plus sterility and endotoxin screening, before release. The Certificate of Analysis for that lot ships with your order.

Growth Hormone

MGF

Mechano Growth Factor

A splice variant of IGF-1 studied for its role in mechanically triggered muscle-tissue signaling.

$35· $17.50/mg

Size

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Pairs with

Bacteriostatic Water

Bacteriostatic Water

Required for reconstitution. Learn more →

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All products sold by One Tap Peptides are intended for laboratory research use only. Not for human consumption. Not intended for animal use. Not intended for diagnostic or therapeutic purposes.